June 27, 2009

Is human height based on how much growth hormone you secrete or genetics?

I was told by my physician that I have excess Growth hormone. Doctors now say height is based on genetics. But Im 18 and am 6'10. Will I keep growin or whats gonna happen. Im healthy.

Genetics is a major factor in determining the height of individuals, though it is far less influential in regard to populations.

Average height is increasingly used as a measure of the health and wellness (standard of living and quality of life) of populations. Attributed as a significant reason for the trend of increasing height in parts of Europe is the egalitarian populations where proper medical care and adequate nutrition are relatively equally distributed. Changes in diet (nutrition) and a general rise in quality of health care and standard of living are the cited factors in the Asian populations. Average height in the United States has remained essentially stagnant since the 1950s. Severe malnutrition is known to cause stunted growth in North Korean, portions of African, certain historical European, and other populations. Diet (in addition to needed nutrients; such things as junk food and attendant health problems such as obesity), exercise, fitness, stress, pollution exposure, sleep patterns, climate (see Allen's rule and Bergmann's Rule for example), and even happiness (psychological well-being) are other factors that can affect growth and final height.

Height is determined by the complex interactive combination of genetics and environment. Genetic potential plus nutrition minus stressors is a basic formula. Genetically speaking, the heights of mother and son and of father and daughter correlate, suggesting that a short mother will more likely bear a shorter son, and tall fathers will have tall daughters. Humans grow fastest (other than in the womb) as infants and toddlers (birth to roughly age 2) and then during the pubertal growth spurt. A slower steady growth velocity occurs throughout childhood between these periods; and some slow, steady, declining growth after the pubertal growth spurt levels off is common. These are also critical periods where stressors such as malnutrition (or even severe child neglect) have the greatest effect. Conversely, if conditions are optimal then growth potential is maximized; and also there is catch-up growth — which can be significant — for those experiencing poor conditions when those conditions improve.

Moreover, the health of a mother throughout her life, especially during her critical periods, and of course during pregnancy, has a role. A healthier child and adult develops a body that is better able to provide optimal prenatal conditions. The pregnant mother's health is important as gestation is itself a critical period for an embryo/fetus, though some problems affecting height during this period are resolved by catch-up growth assuming childhood conditions are good. Thus, there is an accumulative generation effect such that nutrition and health over generations influences the height of descendants to varying degrees.

The precise relationship between genetics and environment and exact role of genetics itself is complex and uncertain. Human height is both of moderately high phenotypic plasticity and is highly heritable. Height is a multigenic trait. There are substantial relationships in the heights among biological families; the heights of parents and family are a good predictor for the height of their children. Environmental influences are most pronounced if they are highly favorable or unfavorable to growth, especially when occurring during critical periods and when continuing multigenerationally. Genetic profile (genotype) provides potentialities or proclivities which interact with environmental factors throughout the period of growth resulting (phenotype) in final adult height. Essentially, the developing body devotes energy to growth after other bodily functions are satisfied.

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